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Essentials 5 in 1 DR Multivitamin 120 vcaps

$ 54.95


  • Essentials 5 in 1 DR (Delayed Release) is our premier , # 1 selling, multi-vitamin-mineral rich product.
  • Designed specifically for maximum hormonal and metabolic activation in one bottle.
  • Most absorbable forms of B-Complex vitamins.
Each Product is a Month's Supply


Delayed Release Therapeutic Multivitamin

Essentials 5 in 1 DR (Delayed Release) is  our flagship, top-selling multi-vitamin-mineral powerhouse. Meticulously crafted to harness the latest advancements in nutritional science, this formula stands as a testament to our commitment to your optimal health and vitality. Designed with precision and backed by extensive research, each nutrient in Essentials 5 in 1 DR is carefully formulated for maximum bioavailability and synergy. From hormonal and metabolic activation to antioxidant support, every capsule is packed with essential vitamins and minerals to fuel your body's needs.

What sets Essentials 5 in 1 DR apart is its innovative delayed release capsules, engineered to minimize or even eliminate gastric side effects often associated with multivitamin intake. Say goodbye to discomfort and hello to seamless absorption, ensuring you experience the full benefits of this comprehensive formula. Why clutter your supplement regimen with multiple bottles when Essentials 5 in 1 DR offers everything you need in one convenient capsule? 

With its complete multinutrient profile, this formula virtually eliminates the need for additional supplemental Vitamin B, Vitamin E, Vitamin A, Vitamin K, and extra minerals.Elevate your wellness journey with MD Prescriptives Essentials 5 in 1 DR – the ultimate solution for optimal hormonal and metabolic activation, all encapsulated in one bottle.

Specific features include:

  • Vitamin A complex - Includes a complete spectrum of beta-carotene and mixed carotenoids. It is a completely natural form derived from the pristine seas of the South Pacific.*
  • Activated B-vitamin complex - Each B vitamin is in its co-enzymated format for optimal bio-utilization. For example, our folic acid is present in Essentials 5 in 1 DR as methylenetetrahydrofolate (MTHFR), rendering this product safe for deficient-methylators. Dosages used eliminate the need for stress-B-complex.*
  • Vitamin C complex - In a very gentle form for the gastrointestinal system. It is also combined with a full spectrum natural citrus bioflavonoids which optimizes utilization.*
  • Vitamin E complex - Synergistically active blend of oil soluble Alpha-Tocopherol, Gamma-Tocopherol and Sesame lignans, plus water soluble Vitamin E succinate (d-alpha tocopheryl acid succinate or alpha-TS). This powerful combination downregulates NF-KB, a primary inducer of inflammation, and enhances benefits of hyperthermia treatments. However, Alpha-Tocopherol alone is susceptible to becoming deactivated by free radicals without Gamma-Tocopherol. Gamma-Tocopherol is a more effective trap than Alpha-Tocopherol for reactive nitrogen oxides, which are toxic to the body. And Sesame lignans add to this synergism by their strong anti-inflammatory (i.e., downregulates NF-KB), lipid-lowering and anti-plaque effects.*
  • Vitamin K2 - Is critical for bone building and breaking apart unhealthy plaque. Essentials 5 in 1 DR and our other multi-nutrient formula Daily Two both contain Vitamin K2, making them the exclusive leaders in the field of multi-vitamin-mineral formulas due to their broad-spectrum mineral-rich, synergistic bioavailability.*
    Albion’s TRAACS® Chelated Minerals: A daily serving of Essentials 5 in 1 DR contains twice the amounts of Albion's TRAAC® minerals as found in our Daily Two formula. Clinically proven, chemically validated mineral amino acid chelates. They represent the gold standard in patented, pharmaceutical grade mineral chelates. Every TRAACS® mineral compound is validated and “fingerprinted” to ensure lot-to-lot conformity to Albion’s high standards.
  • TRAACS® mineral amino acid chelates deliver the following measurable results: 1. Highly bioavailable and easily digested; 2. Safe, predictable and effective; 3. Stable in acidic environments; 4. Hypoallergenic, Kosher-Pareve and vegetarian friendly.*
  • Benfotiamine helps reduce advanced glycation end-products (AGEs) plus calms the inflammatory arachidonic acid pathways by promoting healthy production levels of PGE2, TXB2, COX-2 and LOX-5 by macrophages.*
  • Standard Dosage: Take four (4) capsules daily in divided doses with meals.*
  • These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.


  1. Marini NJ, et al. The prevalence of folate-remedial MTHFR enzyme variants in humans. PNAS. 2008;105:8055-60.
  2.  Deme P, Narasimhulu CA, Parthasarathy S. Identification and Evaluation of Anti-Inflammatory Properties of Aqueous Componenets Extracted from Sesame (Sesamum indicum) Oil. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jun 15;1087-1088.
  3.  Fan D, et al. Sesamin Prevents Apoptosis and Inflammation After Experimental Myocardial Infarction by JNK and NF-KB Pathways. Food Funct. 2017 Aug 1;8(8):2875-85.
  4.  Prassad KN, Kumar B, Yan XD, Hanson AJ, Cole WC. Alpha-Tocopheryl succinate, the Most Effective Form of Vitamin E for Adjuvant Cancer Treatment: A Review. J Am Coll Nutr. 2003 Apr;22(2):108-17.
  5. Maric D, et. Al. Multivitamin mineral supplementation in patients with chronic fatigue syndrome. Med Sci Monit. 2014; 20: 47–53.
  6.  Cheng T, Zhu Z, Masuda S, Morcos NC. Effects of multinutrient supplementation on antioxidant defense systems in healthy human beings. J Nutr Biochem. 2001;12(7):388–95.
  7.  Ockerman PA. Antioxidant treatment of chronic fatigue syndrome. Clin Pract Altern Med. 2000;1:88–91.
  8.  Heaps LC, Peters TJ, et al. Vitamin B status in patients with chronic fatigue syndrome. J R Soc Med. 1999 Apr; 92(4): 183–5.Fletcher RH, Fairfield KM. Vitamins for Chronic Disease Prevention in Adults Clinical Applications. JAMA. 2002;287(23):3127-29. Martin R, Ogston S, Evans J. Effects of vitamin and mineral supplementation on symptoms associated with chronic fatigue syndrome with Coxsackie B antibodies. J Nutr Med. 1994;4:11–23.
  9.  Barringer TA, et al. Effect of a multivitamin and mineral supplement on infection and quality of life: A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2003 Mar 4;138:365-71.
  10. Fawzi W, Stampfer MJ. A role for multivitamins in infection? Ann Intern Med. 2003 Mar 4;138:430-1.
  11.  McKay DL, Perrone G, Rasmussen H, Dallal G, Blumberg JB, Multivitamin/mineral supplementation improves plasma B-vitamin status and homocysteine concentration in healthy older adults consuming a folate-fortified diet. J Nutr. 2000 Dec;130(12):3090-6.
  12.  Shoeb M, Ramana KV. Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages. Free Radic Biol Med. 2012;52(1):182–190. oi:10.1016/j.freeradbiomed.2011.10.444
  13.  Balakumar P, et al. The Multifaceted Therapeutic Potential of Benfotiamine. Pharmacol Res. 2010 Jun;61(6):482-8. doi: 10.1016/j.phrs.2010.02.008.
  14.  See:

Customer Reviews
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United States United States

Good stuff

Jogesh P.
United States United States

Review of Essentials 5 in 1 DR

I have found Essentials 5 in 1 to be a great supplement suiting my health needs

David L.
United States United States

Product is excellent! Shipping is suspect! Last single shipment came in very good condition. The previous double order arrived with one glass container broken, glass throughout the pills. It took some sifting to retrace the pills.I noticed the shipping box was different and poorly prepared

Linda S.
United States United States

The best

I’ve used them for years and compared them to others. I took my bottle to health & vitamin stores to compare ingredients and compared online. I am satisfied these are the best.

Judy S.
United States United States

Worst customer service ever

After 3 emails, one phone call and multiple text messages they were not able to help me sign in to change my subscription account.

Deborah B.
United States United States

Best Mutivitamin

This vitamin has excellent absorption. Although they are expensive they are worth the cost..

Tiffany W.
United States United States

horrible website ordering platforem

Problem with the website ordering platform that resulted in product being sent to wrong address.

United States United States

These are AMAZING!!

I take these twice a day and they have made me feel so much better full of energy. My nails are growing. All my labs at my doctors are back to normal. I just love these.

Jill G.
United States United States

Essentials 5 in 1 Multi is a Must Have in your supplement regime

I have used this product over a year and I feel it is a significant, important and effective contribution to my overall good health. The percentage of ingredients compared to other brands is higher and keeps me from having to take many other supplements to compensate for any deficits.

Shelve B.
United States United States

Contains selenium

This is a very good vitamin but I was shocked to just realize this vitamin has a high content of selenium which makes you loose hair. Thyroid patients loose hair from the disease already. I am going to have to change multi vitamins.

United States United States

Love these!

They make me feel like I have more energy.

Amadita S.
United States United States

Essential 5 in 1 dr

Did not receive my order



For people who have difficulty methylating B vitamins, this multi has B available in a form they can use. I don't have to buy a separate B vitamin since this important nutrient is already in this multi. I am very happy about which vitamins are covered in this multi and that they are in a bioavailable form.

Dr. Sangeeta Pati


Initially my patients were going home with 5 bottles to activate their thyroid, adrenal and insulin hormones. Essentials 5 in 1 was designed specifically to activate these hormones in one bottle. Patients say, " There is no other supplement that gives me the energy boost I get from these." "As soon as I used this, I felt the difference."